“I think it will be a very effective vaccine. That’s my prediction,” said Moncef Slaoui, chief adviser to Operation Warp Speed. “My personal opinion, based on my experience and the biology of this virus, I think this vaccine will be very effective. I wouldn’t be surprised if 90 percent. [range]. ”
Slaoui, an immunologist, previously led the GlaxoSmithKline vaccine program, where he led the development of five major new vaccines.
He said vaccines by 2021 would be enough to “ideally” vaccinate all Americans. Mid, but perhaps not until 2021. The end.
Slaoui spoke with CNN senior medical correspondent Elizabeth Cohen on Thursday during a visit to the Covid-19 vaccine clinical trial site in Savannah, Georgia. It was his first television interview since he joined Operation Warp Speed in May.
When will everyone be vaccinated?
“The best result we’ve ever done is measles, which is 97 to 98 percent effective,” said Fauci, director of the National Institute of Allergies and Infectious Diseases. “It would be wonderful if we got there. I don’t think we will do that. I would reconcile [a] 70, 75% effective vaccine ”.
The effectiveness of vaccines varies. According to the U.S. Centers for Disease Control and Prevention, the total polio vaccine cycle is between 99% and 100% effective; Total vaccination against diphtheria, tetanus and pertussis is 80-90%. effective, and the flu stroke is 40-60 percent.
Slaoui added that the Covid-19 vaccine “may require booster vaccination” after the primary vaccination “every two years or every three years”.
Slaoui said he hoped to “probably get several tens of millions of doses” of the vaccine in December this year or January next year, and that it will reach high-risk individuals because “we won’t have doses for the entire U.S. population on the first day.”
High-risk individuals include the elderly and individuals with health disorders such as hypertension, diabetes, and cardiovascular disease.
Slaoui said he was “optimistic.” All Americans will be vaccinated by 2021. End, but ideally by 2021. Middle.
“That is our goal,” he said.
Vaccine trials are moving at a record pace
Operation Warp Speed is funding eight vaccines, Slaoui said.
He said five of them are already in Phase 3 clinical trials or will begin by the end of September. The Phase 3 study is the last round of testing prior to vaccination to regulators and may be placed on the market. Each phase 3 study of Covid-19 will involve 30,000 subjects.
“They are all different vaccines. In fact, they spread very quickly,” Slaoui said, noting that the virus was detected just six months ago. “I’ve been doing this for 30 years and the fastest thing I can ever remember, which went from discovery to third phase testing, was in four years.”
Moderna and Pfizer vaccines are phase 3 in the US, and AstraZeneca vaccines are in phase 3 trials in the United Kingdom, Brazil and South Africa. Phase 3 trials of this vaccine in the U.S. are expected to begin in August.
Two more companies, Johnson & Johnson and Novavax, are scheduled to begin testing Phase 3 vaccines in September, he added.
Slaoui did not name the other three vaccines that will receive funding from Operation Warp Speed.
CNN’s John Bonifield and Dana Vigue contributed to this report.